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Postdoctoral Position

Molecular cell biology, epigenetics and synthetic genomics (Full-Time)

Start date: negotiable, as early as September 2026 is possible

Location: Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany

Writing, rewriting, and engineering genomes are at the forefront of modern biological and biomedical research. However, our ability to synthetically design and interrogate the epigenome remains limited. One major research focus of the Center for Synthetic Genomics (SynGen) at KIT is the rational engineering of epigenetic features in complex genomes, especially at repetitive regions of centromeres. We are seeking to fill a Carl Zeiss Stiftung–funded academic postdoctoral position in the research group of Prof. Dr. Sylvia Erhardt.
Prof. Sylvia Erhardt
KIT - Zoological Institute (ZOO)

The project aims to develop and functionally validate synthetic pericentromeric DNA sequences by bridging genome engineering and computational analysis.

 

Research Environment​

The successful candidate will join a highly interactive and interdisciplinary research environment at KIT and Center SynGen – with research groups at Karlsruhe, Heidelberg and Mainz. The appointed Bridging Scientist will connect the DNA unit of VirtMat with computational scientists and wet-lab experimentalists in molecular and cell biology. The position focuses on translating genomic design concepts into functional experimental validation.

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Candidate Profile​

We seek highly motivated and collaborative scientists who combine hands-on experimental experience in mammalian cells with bioinformatic expertise. Applicants should have a strong background in molecular biology and substantial competence in at least two of the following areas:

 

  • Functional genomics and computational data analysis

  • Bioinformatics applied to genomic and epigenomic datasets

  • Epigenetics, chromatin biology, and RNA biology

  • Genome engineering or synthetic biology in mammalian cell models

  • Cell biology, microscopy, and biochemical techniques

 

Requirements​

  • PhD degree (completed by the start date) in molecular biology, cell biology, biochemistry, genetics, bioengineering, or a related discipline

  • Demonstrated scientific productivity and independence

  • Strong enthusiasm for interdisciplinary and collaborative research

  • Excellent written and spoken communication skills in English

 

Application Materials (submit the following documents as a single PDF)​

  • A cover letter outlining research interests and motivation

  • Curriculum vitae (including a summary of previous research achievements)

  • Contact details of 2–3 referees

 

How to Apply​

Please email applications to Prof. Dr. Sylvia Erhardt: sylvia.erhardt@kit.edu

* Applications will be reviewed on a rolling basis until the position is filled.

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