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Center SynGen Mitglieder

Dr. rer. nat. Marco Binder

DKFZ Heidelberg

Interests: Cell-intrinsic immunity, innate immunity, virus-host interactions, virus-associated carcinogenesis, human virome, virome-host interactions, viral diversity

Prof. Dr. rer. nat. Benedikt Brors

DKFZ Heidelberg


Interests: Computational biology, bioinformatics, cancer genomics, cancer epigenomics, tumor immunology

Prof. Dr. Andreas Diepold

KIT - Institute for Applied Biosciences (IAB)

Interests: Bacterial secretion systems, host-pathogen-interaction, membrane transport,
synthetic microbiology

Prof. Sylvia Erhardt, PhD

KIT - Zoological Institute (ZOO)

Zoological Institute; KIT- IBCS-FMS

Interests: Epigenetics, epitranscriptomics, centromere and chromatin biology

Prof. Dr. Kerstin Göpfrich

ZMBH, Heidelberg University

Interests: Synthetic cells, DNA/RNA nanotechnology, RNA origami, biophysics, synthetic immunology

Prof. Dr. Dirk Grimm

Medical Faculty and Faculty of Engineering

Sciences, Heidelberg University; BioQuant, CIID

Interests: Gene therapy, viral vectors, translational research, gene editing, genome engineering

Prof. Lennart Hilbert, PhD

KIT - Institute of Biological and Chemical

Systems (IBCS-FMS) & KIT-ZOO

Interests: Natural/artificial DNA systems, 3D genome organization, transcription control, systems biology, biophysics, light microscopy, image processing, quantitative/computational biology

Dr. Mariana Kozlowska

KIT - Institute of Nanotechnology (INT)

Interests: Multiscale simulations, biophysics, protein-DNA complexes, structuring of soft matter, materials design, advanced programmable systems

Dr. Moritz Mall

DKFZ Heidelberg

HITBR, ZI Mannheim

Interests: Cellular plasticity, cell fate engineering, disease modeling, transcriptional networks, stem cell biology, cancer neuroscience

Prof. Dr. Dominik Niopek

IPMB, Heidelberg University

Interests: Protein engineering, genome editing, directed evolution, synthetic biology

Prof. Dr. Veronique Orian-Rousseau

KIT - Institute of Biological and

Chemical Systems – Functional Molecular Systems (IBCS-FMS)

Interests: cancer, tumor microenvironment, immune regulation, organoids, tumoroids

Prof. Dr. James P. Sáenz

ZMBH, Universität Heidelberg

Interests: Synthetic membrane biology, genomically minimal cells, lipid biochemistry, synthesis and origin of life

Prof. Dr. Daniel Schindler

ZMBH, Heidelberg University

Max Planck Institute for Terrestrial Microbiology, Marburg; SYNMIKRO

Interests: Synthetic biology, synthetic genomics, microbiology, molecular biology, genome architecture and evolution

Dr. Iliya D. Stoev

KIT - Institute of Biological and

Chemical Systems – Functional Molecular Systems (IBCS-FMS)

Interests: DNA nanotechnology, DNA hydrogels, functional sequence-programmable materials, microrheology, viscoelasticity, data storage, information processing

Prof. Dr. Hans-Achim Wagenknecht

KIT

Institute of Organic Chemistry

Interests: Bioorganic chemistry: synthetic nucleic acids and peptide chemistry. Functional nucleic acid architectures: fluorescence, electron & energy transfer, multichromophores, photo-DNAzymes, DNA-carbon nanotube & DNA-nanoparticle conjugates, RNA labelling

Prof. Dr. Stefan Wölfl

Institut für Pharmazie und Molekulare

Biotechnologie (IPMB), Universität Heidelberg

Interests: Microfluidic tissue culture, organ on chip, cancer cell metabolism, basic cell metabolism (from yeast to human cells), drug discovery and validation, cellular reprograming and differentiation

Dr. Dr. med. Franziska Blaeschke

DKFZ

KiTZ; UKHD

Interests: Genetic engineering, CRISPR screens, CAR T cells

Prof. Dr. Maryam Chaib De Mares

Departamento de Biología,

Facultad de Ciencias - Universidad Nacional de Colombia, Sede Bogotá

Interests: Microbial systems biology, interspecies molecular cross-talk, synthetic biology, computational biology, evolution

Dr. Carmen M. Domínguez

KIT

Institute for Biological Interfaces 1 (IBG-1)

Interests: DNA nanotechnology, biophysics

Prof. Dr. med. Marc Freichel

DKFZ Heidelberg, UKHD

Interests: Gene editing, calcium, pharmacology, ion channels, hiPSC organoids

Dr. Ralph Grand

ZMBH, Heidelberg University

Interests: Mammalian gene regulation, functional genomics, synthetic biology

Prof. Dr. Nora Heinzelmann

IMSEAM Heidelberg

Institute for Philosophy, Heidelberg

Interests: Ethics, moral psychology

Prof. Dr.-Ing. Dirk Holtmann

KIT - Process Engineering in Life Sciences

(BLT) & KIT-IKFT

Interests: Holistic process development — from genes to processes, enzyme catalysis, electro-biotechnology and CO₂ conversion

Prof. Dr. Moritz Kreysing

KIT - Institute of Biological and Chemical

Systems (IBCS-FMS)

Biophotonics, Biophysics, Micro-Robotics

Prof. Dr. Miha Modic

KIT - Zoological Institute (ZOO)

Interests: RNA-protein interaction networks, synthetic genomics & genome engineering, deep learning for RNA function prediction, programmable RNA tools, spatial RNA biology, stem cells, early development & embryonic gene regulation

Dr. Karol Nowicki-Osuch

DKFZ Heidelberg

DKFZ Hector Cancer Institute at the University Medical Center Mannheim

Interests: Cancer genomics, interception, initiation, and detection, cellular and molecular biology, single cell DNA and RNA sequencing, scDNA-seq, scRNA-seq, organoids, organ-on-chip

Prof. Dr. Gislene Pereira

COS

DKFZ Heidelberg, ZMBH

Interests: Cell biology, yeast synthetic biology, centrosomes/cilia, cell cycle

Dr. Alexander Sasse

ZMBH, Heidelberg University

Interests: Deep learning for regulatory genomics, gene regulation, cis-regulatory elements

Dr. rer. Nat. Maximilian Sprang

UMC Mainz

JGU Mainz (IQCB)

Interests: Genomics, machine learning, artificial intelligence, sequence design

Dr. Duran Sürün

Pharmakological Institut,

Heidelberg University

Interests: Genome editing, directed evolution, protein engineering, gene therapy, synthetic genomics

Dr. Pei-Chi Wei

DKFZ Heidelberg

IZN, Heidelberg University

Interests: Cancer genomics, synthetic genomics, tumor evolution, transgenic models

Prof. Dr. Michael Boutros

Medical Faculty, Heidelberg University

DKFZ

Interests: Signaling networks, cancer genomics, genetic interactions, high-throughput screening, organoid models

Dr. Viet Loan Dao Thi

UKHD

Interests: Hepatitis E virus, stem cell culture models, molecular virology

Prof. Dr. med. Georg Daniel Dürr

Universitätsmedizin Mainz

Interests: Myocardial injury, ischemia/reperfusion, hibernating myocardium, cell implantation, epigenetic modification, RNA-nanoparticles

Prof. Dr. Eileen Furlong

EMBL

Interests: Genome biology, developmental regulatory genomics

Dr. Pranas Grigaitis

KIT

Institute for Biological Interfaces (IBG-5)

Interests: Synthetic metabolism, economic principles in cell biology, microbial physiology

Dr. Konrad Herbst

ZMBH, Heidelberg University


Interests: Synthetic biology and molecular tool development, microbial systems biology, lab automation, computational biology, genome structure and function

Prof. Dr. Michael Knop

ZMBH, Heidelberg University

FSP-A; DKFZ

Interests: Systems biology, genetics, proteostasis, meiosis and genome recombination, evolution

Prof. Dr. Edward A. Lemke

JGU Mainz

IMB Mainz

Interests: Intrinsically disordered proteins, single molecule biophysics, genetic code expansion, nanoscopic, chemical biology, synthetic biology

Dr. Sergio David Moreno Velasquez

University Hospital Heidelberg

Department of Infectious Diseases, Virology, Section Viral Vectors

Interests: Viral vectors, genomics, synthetic gene circuits

Prof. Dr. F. Nina Papavasiliou

DKFZ

Interests: Immune diversity, deaminases, trypanosoma, delivery, antibody development

PD Dr. Kersten S. Rabe

KIT

Institute for Biological Interfaces 1 (IBG-1)

Interests: Biocatalysis, directed evolution, enzyme engineering, biohybrid systems, whole-cell catalysts, structure-function relationship, integration of natural and artificial systems

Jun-Prof. Dr. Lauren Saunders

COS, Heidelberg University

Interests: Developmental biology, single cell genomics, evolution, neural crest, fish

Prof. Dr. Oliver Stegle

EMBL, DKFZ

Interests: Machine learning, causal inference, gene regulatory networks, spatial and multi-omics, cancer genomics, population genetics and human cohorts

Prof. Dr. F.-Nora Vögtle

ZMBH, Heidelberg University

Network Aging Research, Heidelberg University

Interests: Mitochondrial quality control, mitochondrial diseases

Dr. Sam Wilken

JGU Mainz

Interests: Soft matter, liquid-liquid phase separation, DNA nanotechnology, hyperuniformity

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