As part of the nationwide Boys’ Day and Girls’ Day initiatives, the Center for Synthetic Genomics (Center SynGen) welcomed school students to its sites at the Karlsruhe Institute of Technology (KIT) and Johannes Gutenberg University Mainz, offering hands-on insights into cutting-edge life science research.

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The program introduced students to the fundamentals of molecular biology, including DNA structure, chromatin organization, and the flow of genetic information from genes to proteins. Building on this foundation, participants explored advanced topics in synthetic genomics, such as genome modification with XNA, minimal genomes, expanded genetic codes, and their potential applications in biotechnology and medicine.

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Students also discovered how computational tools and simulation are used to study molecular interactions. In a 3D cinema session, they examined everyday activities, such as drinking coffee, from a physiological perspective, highlighting the connections between biology, technology, and society.

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A major highlight was the hands-on laboratory work. Guided by researchers, participants used microscopes, observed zebrafish embryos, and isolated their own DNA. These activities provided an authentic glimpse into experimental and computational research at Center SynGen.

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Throughout the day, students spoke with group leaders, scientists, and laboratory technicians about academic pathways and careers in research. Their feedback reflected both excitement and curiosity: “I really liked getting an insight into research and the labs,” and “Learning what DNA is and how it is structured - and working with the big microscope - was amazing!”

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Through its participation in Boys’ Day and Girls’ Day, Center SynGen demonstrates its commitment to science education, equal opportunities, and inspiring young people to explore scientific careers beyond traditional gender stereotypes.